Extracellular matrix: Forum introduction

نویسنده

  • Daniel D Carson
چکیده

The extracellular matrix (ECM) is now appreciated as a key regulator of cell and tissue behavior [1,2]. Support for this notion has been derived from correlative studies demonstrating large changes in the composition and distribution of extracellular matrix components during tissue development, differentiation and in response to hormone/growth factor/cytokine influences. In addition, a variety of functional studies demonstrate ECM-dependent cellular responses in vitro while genetic approaches clearly demonstrate critical requirements for genes encoding ECM components or modifiers of ECM, e.g., metalloproteases, in a wide variety of processes in vivo [3,4].

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عنوان ژورنال:
  • Reproductive biology and endocrinology : RB&E

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2004