Extracellular matrix: Forum introduction
نویسنده
چکیده
The extracellular matrix (ECM) is now appreciated as a key regulator of cell and tissue behavior [1,2]. Support for this notion has been derived from correlative studies demonstrating large changes in the composition and distribution of extracellular matrix components during tissue development, differentiation and in response to hormone/growth factor/cytokine influences. In addition, a variety of functional studies demonstrate ECM-dependent cellular responses in vitro while genetic approaches clearly demonstrate critical requirements for genes encoding ECM components or modifiers of ECM, e.g., metalloproteases, in a wide variety of processes in vivo [3,4].
منابع مشابه
Effect of extracellular matrix on testosterone production during in vitro culture of bovine testicular cells
Testosterone is believed to play a significant role in spermatogenesis, but its contribution to the process of spermatogenesis is not completely understood. Given that extracellular matrix (ECM) facilitates differentiation of spermatogonial stem cells (SSCs) during culture, the present study was conducted to elucidate whether testosterone contribute to the permissive effect of ECM on SSCs diffe...
متن کاملThe effect of interval training and consumption of Urtica dioica hydroalcoholic extract on Heat shock protein 70 and Extracellular matrix metalloproteinase inducer in C57 rats with melanoma cancer
Introduction: It has been suggested that targeted therapy of growth and immune factors may lead to more effective inhibition of tumor proliferation and recurrence in melanoma cancer. The aim of this study was to investigate the effect of interval training and consumption of Urtica dioica hydroalcoholic extract on Heat shock protein 70 (HSP70) and Extracellular matrix metalloproteinase inducer (...
متن کاملIn vitro histological investigation of interactions between rat decellularized large intestine scaffold and human adipose derived mesenchymal stem cells
The aim of this study was to investigate the interactions between rat intestine decellularized scaffold and human adipose derived mesenchymal stem cells. Rat large intestine was dissected in fragments and decellularized by physicochemical methods. The scaffolds were loaded by human adipose derived mesenchymal stem cells expressing green fluorescent protein. Microscopic sections were prepared fr...
متن کاملPreliminary Results of a Consecutive Series of Large & Massive Rotator Cuff Tears Treated with Arthroscopic Rotator Cuff Repairs Augmented with Extracellular Matrix
Background: Recurrence rate of rotator cuff tears is still high despite the improvements of surgical techniques, materials used and a better knowledge of the healing process of the rotator cuff tendons. Large to massive rotator cuff tears are particularly associated with a high failure rate, especially in elderly. Augmentation of rotator cuff repairs with extracellular matrix or synthetic patc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Reproductive biology and endocrinology : RB&E
دوره 2 شماره
صفحات -
تاریخ انتشار 2004